Reactome: A Curated Pathway Database

Cystine-bonded Proinsulin translocates from the endoplasmic reticulum to the Golgi (R-HSA-265010) [Homo sapiens]

Black Box Event

Proinsulin in the endoplasmic reticulum moves to the Golgi apparatus via vesicles that bud from the endoplasmic reticulum.

Additional Information
Compartment ER to Golgi transport vesicle
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Literature References
pubMedId Title Journal Year
3896518 Direct identification of prohormone conversion site in insulin-secreting cells Cell 1985
9631292 The role of assembly in insulin's biosynthesis Curr Opin Struct Biol 1998