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Signaling by NOTCH1 HD Domain Mutants in Cancer

Stable Identifier
R-HSA-2691230
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

NOTCH1 heterodimerization domain mutations are frequently found in T-cell acute lymphoblastic leukemia (T-ALL) (Weng et al. 2004) and result in constitutive activity of NOTCH1 mutants (Malecki et al. 2006).

Participants
Participant Of