Reactome: A Curated Pathway Database

Non-integrin membrane-ECM interactions (R-HSA-3000171) [Homo sapiens]


Several non-integrin membrane proteins interact with extracellular matrix proteins. Transmembrane proteoglycans may associate with integrins and growth factor receptors to influence their function, or they can signal independently, often influencing the actin cytoskeleton.

Literature References
pubMedId Title Journal Year
15039999 From cell-ECM interactions to tissue engineering J. Cell. Physiol. 2004
20565253 Transmembrane signaling proteoglycans Annu. Rev. Cell Dev. Biol. 2010