Reactome: A Curated Pathway Database
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Non-integrin membrane-ECM interactions

Stable Identifier
R-HSA-3000171
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

Several non-integrin membrane proteins interact with extracellular matrix proteins. Transmembrane proteoglycans may associate with integrins and growth factor receptors to influence their function, or they can signal independently, often influencing the actin cytoskeleton.

Literature References
PubMed ID Title Journal Year
15039999 From cell-ECM interactions to tissue engineering J. Cell. Physiol. 2004
20565253 Transmembrane signaling proteoglycans Annu. Rev. Cell Dev. Biol. 2010
Participants
Participant Of
Orthologous Events