HIV Virion Budding

Stable Identifier
R-HSA-3159227
Type
Reaction [omitted]
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
extracellular region, plasma membrane
ReviewStatus
5/5
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HIV Virion Budding
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The events that lead to the viral component assembly and the recruitment of the ESCRT host machinery are well-characterized. The exact steps that release the immature viral particle are not. Membrane fission is an energy intensive process and an active area of study.
Literature References
PubMed ID Title Journal Year
22762019 HIV-1 Assembly, Budding, and Maturation

Sundquist, WI, Kräusslich, HG

Cold Spring Harb Perspect Med 2012
19527882 The cell biology of HIV-1 virion genesis

Bieniasz, PD

Cell Host Microbe 2009
Participants
Input
Output
Participates
as an event of
This event is regulated
Requirements
Disease
Name Identifier Synonyms
Human immunodeficiency virus infectious disease DOID:526 HIV infection
Authored
Gillespie, ME  (2013-03-07)
Reviewed
Dube, M  (2013-05-21)
Created
Gillespie, ME  (2013-02-20)
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