Reactome: A Curated Pathway Database

Retromer recycles WLS to the Golgi (R-HSA-3247836) [Homo sapiens]

Black Box Event

Retromer is believed to escort WLS from the early endosome back to the Golgi for subsequent rounds of WNT secretion (reviewed in Johannes and Wunder, 2011; Willert and Nusse, 2012 ).

Additional Information
Compartment Golgi membrane , early endosome membrane
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Literature References
pubMedId Title Journal Year
21725318 The SNXy flavours of endosomal sorting Nat. Cell Biol. 2011
22952392 Wnt proteins Cold Spring Harb Perspect Biol 2012