Reactome: A Curated Pathway Database
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SMAD4 K428R

Stable Identifier
R-HSA-3311001
Type
Protein
Species
Homo sapiens
Compartment
Synonyms
SMAD4 Lys428Arg
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
SMAD4, DPC4, MADH4
Chain
chain:1-552
Reference Genes
Reference Transcript
Other Identifiers
 0000540341  11725360_a_at  11725361_s_at  11725362_x_at  11725363_s_at
 11744679_a_at  11750827_a_at  11753117_a_at  16852354  1DD1
 1G88  1MR1  1U7F  1U7V  1YGS
 202526_at  202527_s_at  235725_at  36953_at  4089
 46885_at  509_at  510_g_at  57902_at  58962_at
 74813_at  A0A024R274  A_14_P134632  A_19_P00323665  A_19_P00804817
 A_19_P00812250  A_23_P27346  AAA91041  AAC03051  AAH02379
 BAF83459  CAB002312  CCDS11950  EAW62985  EAW62986
 EAW62987  ENSG00000141646  ENSP00000341551  ENSP00000381452  ENST00000342988
 ENST00000398417  EntrezGene:4089  GE887174  HGNC:6770  HPA019154
 Hs.75862  ILMN_1741477  ILMN_1842785  IPR001132  IPR003619
 IPR008984  IPR013019  LRG_318  LRG_318t1  MIM:600993
 NM_005359  NP_005350  PF03165  PF03166  PH_hs_0004380
 SM00523  SM00524  SMAD4  SMAD4-001  SMAD4-201
 U44378_at  uc010xdp.3  uc060pfa.1  UPI0000053431
Participant Of
Other forms of this molecule
Modified Residues
Name Coordinate Modification PsiMod
L-lysine residue 428 replaced with L-arginine 428
Disease
Diseases
Name Identifier Synonyms
bile duct carcinoma 4897
cancer 162 [malignant tumor, malignant neoplasm, primary cancer]
Cross References
RefSeq
UCSC human
COSMIC
GeneCards
DOCK Blaster
PRO
Protein Data Bank
Interactors
Confidence Score Interactor Accession Interactor Name Evidence (IntAct)
0.957 Q15796 SMAD2_HUMAN 21
0.957 P84022 SMAD3_HUMAN 18
0.878 P12755 SKI_HUMAN 12
0.867 Q15797 SMAD1_HUMAN 7
0.748 Q9UPN9 TRI33_HUMAN 6
0.721 P63279 UBC9_HUMAN 4
0.719 Q9UBE8 NLK_HUMAN 6
0.609 P17676 CEBPB_HUMAN 2
0.602 Q92988 DLX4_HUMAN 5
0.602 P70398 USP9X_MOUSE 4
0.576 O43524 FOXO3_HUMAN 4
0.556 Q8WWW0 RASF5_HUMAN 3
0.556 P61968 LMO4_HUMAN 3
0.553 Q6VMQ6 MCAF1_HUMAN 2
0.553 O75925 PIAS1_HUMAN 2
0.547 Q13485 SMAD4_HUMAN 3
0.547 Q9NPI6 DCP1A_HUMAN 2
0.547 O15198 SMAD9_HUMAN 2
0.547 P12757 SKIL_HUMAN 3
0.527 SMAD7 ENSG00000101665 3
0.524 Q9UI36 DACH1_HUMAN 3
0.508 P23769 GATA2_HUMAN 2
0.499 P70056 FOXH1_XENLA 2
0.488 Q96F07 CYFP2_HUMAN 2