Reactome: A Curated Pathway Database

Regulation of HSF1-mediated heat shock response (R-HSA-3371453)

Species Homo sapiens

Summation

The ability of HSF1 to respond to cellular stresses is under negative regulation by chaperones, modulation of nucleocytoplasmic shuttling, post-translational modifications and transition from monomeric to trimeric state.

Locations in the PathwayBrowser
Additional Information
GO Biological Process regulation of cellular response to heat (1900034)
Literature References
pubMedId Title Journal Year
7623826 Multiple layers of regulation of human heat shock transcription factor 1 Mol. Cell. Biol. 1995