There will be a maintenance on OICR IT systems starting Friday Dec 15 at 6PM EST until midnight Sunday Dec 17; Reactome will be affected by this downtime

Service under maintenance from Friday Dec 15 at 6PM EST until midnight Sunday Dec 17

Class A/1 (Rhodopsin-like receptors)

Stable Identifier
Homo sapiens
Locations in the PathwayBrowser

Rhodopsin-like receptors (class A/1) are the largest group of GPCRs and are the best studied group from a functional and structural point of view. They show great diversity at the sequence level and thus, can be subdivided into 19 subfamilies (Subfamily A1-19) based on a phylogenetic analysis (Joost P and Methner A, 2002). They represent members which include hormone, light and neurotransmitter receptors and encompass a wide range of functions including many autocrine, paracrine and endocrine processes.

Literature References
PubMed ID Title Journal Year
16902930 The 7 TM G-protein-coupled receptor target family ChemMedChem 2006
Participant Of
Orthologous Events