Reactome: A Curated Pathway Database

Class A/1 (Rhodopsin-like receptors) (R-HSA-373076) [Homo sapiens]


Rhodopsin-like receptors (class A/1) are the largest group of GPCRs and are the best studied group from a functional and structural point of view. They show great diversity at the sequence level and thus, can be subdivided into 19 subfamilies (Subfamily A1-19) based on a phylogenetic analysis (Joost P and Methner A, 2002). They represent members which include hormone, light and neurotransmitter receptors and encompass a wide range of functions including many autocrine, paracrine and endocrine processes.

Literature References
pubMedId Title Journal Year
16902930 The 7 TM G-protein-coupled receptor target family ChemMedChem 2006