Reactome: A Curated Pathway Database

Class B/2 (Secretin family receptors)

Stable Identifier
R-HSA-373080
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

This family is known as Family B (secretin-receptor family, family 2) G-protein-coupled receptors. Family B GPCRs include secretin, calcitonin, parathyroid hormone/parathyroid hormone-related peptides and vasoactive intestinal peptide receptors; all of which activate adenylyl cyclase and the phosphatidyl-inositol-calcium pathway (Harmar AJ, 2001).

Literature References
PubMed ID Title Journal Year
11790261 Family-B G-protein-coupled receptors Genome Biol 2001
Participants
Participant Of
Orthologous Events