Reactome: A Curated Pathway Database

Amine ligand-binding receptors (R-HSA-375280)

Species Homo sapiens

Summation

The class A (rhodopsin-like) GPCRs that bind to classical biogenic amine ligands are annotated here. The amines involved (acetylcholine, adrenaline, noradrenaline, dopamine, serotonin and histamine) can all act as neurotransmitters in humans. The so-called 'trace amines', used when referring to p-tyramine, beta-phenylethylamine, tryptamine and octopamine, can also bind to recently-discovered GPCRs.

Locations in the PathwayBrowser