Reactome: A Curated Pathway Database

Enzymatic degradation of dopamine by COMT

Stable Identifier
R-HSA-379397
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

Dopamine once taken up by the dopamine transporter from the extracellular space into the cytosol is metabolized in a two step reaction to homovanillic acid.The first reaction is catalyzed by catecholamine o-methyl transferase and the subsequent reaction is catalyzed by monoamine oxidase A.

Literature References
Participants
Participant Of
Orthologous Events
Cross References