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Serotonin clearance from the synaptic cleft
Stable Identifier
R-HSA-380615
Type
Pathway
Species
Homo sapiens
Synonyms
Clearance of seratonin, Clearance of serotonin
ReviewStatus
5/5
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Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter clearance (Homo sapiens)
Serotonin clearance from the synaptic cleft (Homo sapiens)
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Serotonergic neurotransmission affects a wide range of behaviors, from food intake and reproductive activity, to sensory processing and motor activity, to cognition and emotion. One such key regulator is the serotonin transporter (5-HTT), which is observed to remove serotonin released into the synaptic cleft.
Participants
Events
SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol
(Homo sapiens)
SLC6A4 binds TCAs and SSRIs
(Homo sapiens)
Metabolism of serotonin
(Homo sapiens)
Participates
as an event of
Neurotransmitter clearance (Homo sapiens)
Orthologous Events
Serotonin clearance from the synaptic cleft (Bos taurus)
Serotonin clearance from the synaptic cleft (Caenorhabditis elegans)
Serotonin clearance from the synaptic cleft (Canis familiaris)
Serotonin clearance from the synaptic cleft (Danio rerio)
Serotonin clearance from the synaptic cleft (Dictyostelium discoideum)
Serotonin clearance from the synaptic cleft (Drosophila melanogaster)
Serotonin clearance from the synaptic cleft (Gallus gallus)
Serotonin clearance from the synaptic cleft (Mus musculus)
Serotonin clearance from the synaptic cleft (Plasmodium falciparum)
Serotonin clearance from the synaptic cleft (Rattus norvegicus)
Serotonin clearance from the synaptic cleft (Saccharomyces cerevisiae)
Serotonin clearance from the synaptic cleft (Schizosaccharomyces pombe)
Serotonin clearance from the synaptic cleft (Sus scrofa)
Serotonin clearance from the synaptic cleft (Xenopus tropicalis)
Authored
Mahajan, SS (2008-01-14)
Reviewed
Restituito, S (2008-11-27)
Created
Mahajan, SS (2008-11-13)
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