Reactome: A Curated Pathway Database

LKB1 forms a trimeric complex with STRAD and MO25

Stable Identifier
R-HSA-380942
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Upon complex formation with STRAD and MO25, LKB1 (also known as serine/threonine kinase 11, STK11) is mostly cytosolic. LKB1 attains 20x activity towards the substrates belonging to the subfamily of AMPK-like kinases (5'AMP-activated protein kinases).

Literature References
Participants
Participant Of
Orthologous Events