Reactome: A Curated Pathway Database

LKB1 forms a trimeric complex with STRAD and MO25 (R-HSA-380942) [Homo sapiens]

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Summation

Upon complex formation with STRAD and MO25, LKB1 (also known as serine/threonine kinase 11, STK11) is mostly cytosolic. LKB1 attains 20x activity towards the substrates belonging to the subfamily of AMPK-like kinases (5'AMP-activated protein kinases).

Additional Information
Compartment cytosol
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