Reactome: A Curated Pathway Database

p-S52-EIF2S1 (R-HSA-381060) [Homo sapiens]

Reference Gene Product
Other forms of this molecule
Additional Information
External reference name EIF2S1
External reference id P05198
Synonyms eIF2-alpha (phosphorylated at Ser52), eIF-2-alpha, translation initiation factor 2 alpha subunit, translation initiation factor 2, subunit 1, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 alpha subunit, EIF- 2alpha
Compartment cytosol
Other Identifiers
 0005720537  1154_at  11716219_a_at  11716220_x_at  11716221_at
 11749910_a_at  11752101_s_at  1965  1KL9  1Q8K
 201142_at  201143_s_at  201144_s_at  39784_at  A_14_P121759
 A_14_P130960  A_24_P356015  A_33_P3402171  AAA52373  AAH02513
 AK312442  BAG35351  BC002513  BX161521  CAB011663
 CAD61953  CCDS9781  CH471061  EAW80933  EAW80934
 EIF2S1  EIF2S1-003  EIF2S1-004  ENSG00000134001  ENSP00000256383
 ENSP00000425299  ENST00000256383  ENST00000466499  EntrezGene:1965  g12803384_3p_a_at
 g4758255_3p_a_at  GE891206  HGNC:3265  HPA064885  Hs.151777
 Hs.151777.0.A3_3p_at  ILMN_1739821  IPR003029  IPR011488  IPR012340
 IPR022967  IPR024054  IPR024055  J02645  J02645_at
 MIM:603907  NM_004094  NP_004085  OTTHUMP00000028404  OTTHUMP00000218025
 PF00575  PF07541  PH_hs_0009146  PH_hs_0049282  Q53XC0
 R-HSA-156827  R-HSA-381042  R-HSA-381119  R-HSA-382551  R-HSA-382556
 R-HSA-392499  R-HSA-72613  R-HSA-72649  R-HSA-72662  R-HSA-72695
 R-HSA-72702  R-HSA-72706  R-HSA-72731  R-HSA-72737  R-HSA-72766
 R-HSA-74160  SM00316  U26032_at  uc001xjg.4  uc059cpd.1
 UPI000000CC43
Secondary Identifiers IF2A_HUMAN
Gene Names EIF2S1, EIF2A
Chain chain:1-315
This entry is a component of:
output
Reference Genes
Database Identifier
dbSNP Gene 1965
CTD Gene 1965
BioGPS Gene 1965
NCBI Gene 1965
ENSEMBL ENSG00000134001
KEGG Gene EIF2S1
Reference Transcripts
Database Identifier
RefSeq NM_004094
Cross References
Database Identifier
RefSeq NP_004085
DOCK Blaster 1Q8K, 1KL9
HMDB_protein HMDBP02276
PRO P05198
GeneCards P05198
UCSC human P05198
Protein Data Bank 1Q8K, 1KL9
This entity regulates
Regulation type Name
PositiveRegulation
ModifiedResidues
Name Coordinate Modification PsiMod Name PsiMod Identifier PsiMod Definition
O-phospho-L-serine at 52 52 O-phospho-L-serine 00046 A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Inferred Entries
Inferred to
Interactions
Confidence Score Interactor Accession Interactor Name Evidences
0.71 P19525 E2AK2 4
0.655 Q9Z2B5 E2AK3 MOUSE 4
0.642 O00571 DDX3X 3
0.59 P20042 IF2B 6
0.499 P78344 IF4G2 2