Reactome: A Curated Pathway Database
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p-S52-EIF2S1

Stable Identifier
R-HSA-381060
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
eIF2-alpha (phosphorylated at Ser52), eIF-2-alpha, translation initiation factor 2 alpha subunit, translation initiation factor 2, subunit 1, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 alpha subunit, EIF- 2alpha, EIF-2A
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
EIF2S1, EIF2A
Chain
chain:1-315
Reference Genes
Reference Transcript
Other Identifiers
 0005720537  1154_at  11716219_a_at  11716220_x_at  11716221_at
 11749910_a_at  11752101_s_at  16785631  1965  1KL9
 1Q8K  201142_at  201143_s_at  201144_s_at  39784_at
 7975224  A_14_P121759  A_14_P130960  A_24_P356015  A_33_P3402171
 AAA52373  AAH02513  AK312442  BAG35351  BC002513
 BX161521  CAB011663  CAD61953  CCDS9781  cg00924576
 cg06724236  cg20908993  cg21926698  cg22792862  cg22868346
 CH471061  EAW80933  EAW80934  EIF2S1  EIF2S1-003
 EIF2S1-004  ENSG00000134001  ENSP00000256383  ENSP00000425299  ENST00000256383
 ENST00000466499  EntrezGene:1965  g12803384_3p_a_at  g4758255_3p_a_at  GE891206
 HGNC:3265  HPA064885  Hs.151777  Hs.151777.0.A3_3p_at  ILMN_1739821
 IPR003029  IPR011488  IPR012340  IPR022967  IPR024054
 IPR024055  J02645  J02645_at  MIM:603907  NM_004094
 NP_004085  PF00575  PF07541  PH_hs_0009146  PH_hs_0049282
 Q53XC0  SM00316  TC14000406.hg  U26032_at  uc001xjg.4
 uc059cpd.1  UPI000000CC43
Participant Of
This entity regulates
Other forms of this molecule
Inferred To
Modified Residues
Name Coordinate Modification PsiMod
O-phospho-L-serine at 52 52
O-phospho-L-serine [MOD:00046] A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
UCSC human
GeneCards
DOCK Blaster
PRO
HMDB_protein
Protein Data Bank
Interactors
Confidence Score Interactor Accession Interactor Name Evidence (IntAct)
0.71 P19525 E2AK2_HUMAN 4
0.655 Q9Z2B5 E2AK3_MOUSE 4
0.642 O00571 DDX3X_HUMAN 3
0.59 P20042 IF2B_HUMAN 6
0.499 P78344 IF4G2_HUMAN 2
0.488 Q9NVM4 ANM7_HUMAN 2
0.488 P12814 ACTN1_HUMAN 4
0.488 Q08AM6 VAC14_HUMAN 2