Reactome: A Curated Pathway Database

p-S52-EIF2S1 (R-HSA-381060) [Homo sapiens]

Reference Gene Product
Other forms of this molecule
Additional Information
External reference name EIF2S1
External reference id P05198
Synonyms eIF2-alpha (phosphorylated at Ser52), eIF-2-alpha, translation initiation factor 2 alpha subunit, translation initiation factor 2, subunit 1, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 alpha subunit, EIF- 2alpha
Compartment cytosol
Other Identifiers
 0005720537  1154_at  11716219_a_at  11716220_x_at  11716221_at
 11749910_a_at  11752101_s_at  1965  1KL9  1Q8K
 201142_at  201143_s_at  201144_s_at  39784_at  A_14_P121759
 A_14_P130960  A_24_P356015  A_33_P3402171  AAA52373  AAH02513
 AK312442  BAG35351  BC002513  BX161521  CAB011663
 CAD61953  CCDS9781  CH471061  EAW80933  EAW80934
 EIF2S1  EIF2S1-003  EIF2S1-004  ENSG00000134001  ENSP00000256383
 ENSP00000425299  ENST00000256383  ENST00000466499  EntrezGene:1965  g12803384_3p_a_at
 g4758255_3p_a_at  GE891206  HGNC:3265  HPA064885  Hs.151777
 Hs.151777.0.A3_3p_at  ILMN_1739821  IPR003029  IPR011488  IPR012340
 IPR022967  IPR024054  IPR024055  J02645  J02645_at
 MIM:603907  NM_004094  NP_004085  OTTHUMP00000028404  OTTHUMP00000218025
 PF00575  PF07541  PH_hs_0009146  PH_hs_0049282  Q53XC0
 R-HSA-156827  R-HSA-381042  R-HSA-381119  R-HSA-382551  R-HSA-382556
 R-HSA-392499  R-HSA-72613  R-HSA-72649  R-HSA-72662  R-HSA-72695
 R-HSA-72702  R-HSA-72706  R-HSA-72731  R-HSA-72737  R-HSA-72766
 R-HSA-74160  SM00316  U26032_at  uc001xjg.4  uc059cpd.1
Secondary Identifiers IF2A_HUMAN
Gene Names EIF2S1, EIF2A
Chain chain:1-315
This entry is a component of:
Reference Genes
Database Identifier
dbSNP Gene 1965
CTD Gene 1965
BioGPS Gene 1965
NCBI Gene 1965
ENSEMBL ENSG00000134001
Reference Transcripts
Database Identifier
RefSeq NM_004094
Cross References
Database Identifier
RefSeq NP_004085
DOCK Blaster 1Q8K, 1KL9
HMDB_protein HMDBP02276
PRO P05198
GeneCards P05198
UCSC human P05198
Protein Data Bank 1Q8K, 1KL9
This entity regulates
Regulation type Name
Name Coordinate Modification PsiMod Name PsiMod Identifier PsiMod Definition
O-phospho-L-serine at 52 52 O-phospho-L-serine 00046 A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Inferred Entries
Inferred to
Confidence Score Interactor Accession Interactor Name Evidence
0.71 P19525 E2AK2_HUMAN 4
0.655 Q9Z2B5 E2AK3_MOUSE 4
0.642 O00571 DDX3X_HUMAN 3
0.59 P20042 IF2B_HUMAN 6
0.499 P78344 IF4G2_HUMAN 2