Reactome: A Curated Pathway Database

p-S52-EIF2S1

Stable Identifier
R-HSA-381060
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
eIF2-alpha (phosphorylated at Ser52), eIF-2-alpha, translation initiation factor 2 alpha subunit, translation initiation factor 2, subunit 1, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 alpha subunit, EIF- 2alpha, EIF-2A
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
EIF2S1, EIF2A
Chain
chain:1-315
Reference Genes
Reference Transcript
Other Identifiers
 0005720537  1154_at  11663  11716219_a_at  11716220_x_at
 11716221_at  11749910_a_at  11752101_s_at  16785631  1965
 1KL9  1Q8K  201142_at  201143_s_at  201144_s_at
 3541138  3541139  3541140  3541141  3541145
 3541146  3541150  3541152  3541155  3541157
 3541161  3541163  3541164  3541165  3541166
 3541167  39784_at  64885  7975224  A_14_P121759
 A_24_P138556  A_24_P356015  A_33_P3402171  AAA52373  AAH02513
 AK312442  BAG35351  BC002513  BX161521  CAB011663
 CAD61953  CCDS9781  CH471061  EAW80933  EAW80934
 EIF2S1  EIF2S1-201  EIF2S1-202  ENSG00000134001  ENSP00000256383
 ENSP00000425299  ENST00000256383  ENST00000466499  EntrezGene:1965  g12803384_3p_a_at
 g4758255_3p_a_at  GE57464  GE891206  GO:0003674  GO:0003676
 GO:0003723  GO:0003743  GO:0005515  GO:0005575  GO:0005576
 GO:0005622  GO:0005623  GO:0005634  GO:0005737  GO:0005829
 GO:0005840  GO:0005844  GO:0005850  GO:0005851  GO:0006412
 GO:0006413  GO:0006417  GO:0006464  GO:0006810  GO:0006950
 GO:0007165  GO:0007568  GO:0008135  GO:0008150  GO:0008219
 GO:0009058  GO:0010494  GO:0016020  GO:0032057  GO:0033290
 GO:0034198  GO:0034605  GO:0034641  GO:0034644  GO:0034976
 GO:0036499  GO:0043022  GO:0043226  GO:0043234  GO:0043558
 GO:0043614  GO:0044207  GO:0046777  GO:0055085  GO:0070062
 GO:0097451  GO:1901216  GO:1905098  GO:1990737  GO:2000676
 HGNC:3265  HPA064885  Hs.151777  Hs.151777.0.A3_3p_at  ILMN_1739821
 IPR003029  IPR011488  IPR012340  IPR022967  IPR024054
 IPR024055  J02645  J02645_at  MIM:603907  NM_004094
 NP_004085  PF00575  PF07541  PH_hs_0009146  Q53XC0
 SM00316  TC14000406.hg  U26032_at  uc001xjg.4  uc059cpd.1
 UPI000000CC43
Participant Of
This entity regulates
Other forms of this molecule
Inferred To
Modified Residues
Name Coordinate Modification PsiMod
O-phospho-L-serine at 52 52
O-phospho-L-serine [MOD:00046] A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
UCSC human
GeneCards
DOCK Blaster
PRO
HMDB Protein
PDB
Interactors
Confidence Score Interactor Accession Interactor Name Evidence (IntAct)
0.71 P19525 E2AK2_HUMAN 4
0.655 Q9Z2B5 E2AK3_MOUSE 4
0.642 O00571 DDX3X_HUMAN 3
0.59 P20042 IF2B_HUMAN 6
0.499 P78344 IF4G2_HUMAN 2
0.488 Q9NVM4 ANM7_HUMAN 2
0.488 P12814 ACTN1_HUMAN 4
0.488 Q08AM6 VAC14_HUMAN 2