Reactome: A Curated Pathway Database

Beta-oxidation of pristanoyl-CoA (R-HSA-389887)

Species Homo sapiens


Pristanoyl-CoA, generated in the peroxisome by alpha-oxidation of dietary phytanic acid, is further catabolized by three cycles of peroxisomal beta-oxidation to yield 4,8-dimethylnonanoyl-CoA, acetyl-CoA and two molecules of propionyl-CoA. These molecules in turn are converted to carnitine conjugates, which can be transported to mitochondria (Wanders and Waterham 2006, Verhoeven et al. 1998, Ferdinandusse et al. 1999).

Locations in the PathwayBrowser
Additional Information
Compartment peroxisomal matrix
GO Biological Process fatty acid beta-oxidation using acyl-CoA oxidase (0033540)