Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA

Stable Identifier
R-HSA-389897
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Peroxisomal 2-methylacyl-CoA racemase (AMACR) catalyzes the isomerization of (2R)-pristanoyl-CoA to form (2S)-pristanoyl-CoA. The active form of the enzyme is a monomer (Schmitz et al. 1995; Amery et al. 2000; Ferdinandusse et al. 2000).
Literature References
PubMed ID Title Journal Year
11060344 Mitochondrial and peroxisomal targeting of 2-methylacyl-CoA racemase in humans

Van Veldhoven, PP, Amery, L, Mannaerts, GP, Fransen, M, De Nys, K

J Lipid Res 2000
11060359 Subcellular localization and physiological role of alpha-methylacyl-CoA racemase

IJlst, L, Denis, S, Wanders, RJA, Dacremont, G, Waterham, HR, Ferdinandusse, S

J Lipid Res 2000
7649182 Purification and characterization of an alpha-methylacyl-CoA racemase from human liver

Fingerhut, R, Conzelmann, E, Albers, C, Schmitz, W

Eur J Biochem 1995
Participants
Participates
Catalyst Activity

alpha-methylacyl-CoA racemase activity of AMACR [peroxisomal matrix]

Orthologous Events
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