Prefoldin mediated transfer of substrate to CCT/TriC

Stable Identifier
R-HSA-389957
Type
Pathway
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Prefoldin mediated transfer of substrate to CCT/TriC
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Unfolded actins and tubulins bound to prefoldin are transferred to CCT via a docking mechanism (McCormack and Willison, 2001).
Literature References
PubMed ID Title Journal Year
11580269 Point mutations in a hinge linking the small and large domains of beta-actin result in trapped folding intermediates bound to cytosolic chaperonin CCT

Carrascosa, JL, Llorca, O, Valpuesta, JM, Willison, KR, McCormack, EA

J Struct Biol 2001
Participants
Events
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as an event of
Authored
Matthews, L  (2008-12-01)
Reviewed
Cowan, NJ  (2009-01-21)
Created
Matthews, L  (2009-01-22)
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