Prefoldin mediated transfer of substrate to CCT/TriC

Stable Identifier
R-HSA-389957
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Unfolded actins and tubulins bound to prefoldin are transferred to CCT via a docking mechanism (McCormack and Willison, 2001).

Literature References
PubMed ID Title Journal Year
11580269 Point mutations in a hinge linking the small and large domains of beta-actin result in trapped folding intermediates bound to cytosolic chaperonin CCT

McCormack, EA, Llorca, O, Carrascosa, JL, Valpuesta, JM, Willison, KR

J Struct Biol 2001
Participants
Participant Of
Authored
Reviewed