Reactome: A Curated Pathway Database

Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding (R-HSA-389958)

Species Homo sapiens


In the case of actin and tubulin folding, and perhaps other substrates, the emerging polypeptide chain is transferred from the ribosome to TRiC via Prefoldin (Vainberg et al., 1998).

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Additional Information
Compartment cytosol
Literature References
pubMedId Title Journal Year
9630229 Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin Cell 1998