Reactome: A Curated Pathway Database

Recruitment of SCAP2 to pSIRP alpha (R-HSA-391157) [Homo sapiens]


SRC-family-associated phosphoprotein 2 (SCAP2) has been shown to bind to SIRP alpha. Evidence from immunoprecipitation experiments performed in COS-7 lysates suggests that the SH3 domain of SCAP2 is involved in the interaction.

Additional Information
Compartment cytosol , plasma membrane
Components of this entry
Input entries
Output entries
Literature References
pubMedId Title Journal Year
10469599 SHPS-1 is a scaffold for assembling distinct adhesion-regulated multi-protein complexes in macrophages Curr Biol 1999