Reactome: A Curated Pathway Database

Recruitment of SCAP2 to pSIRP alpha (R-HSA-391157)

Species Homo sapiens


SRC-family-associated phosphoprotein 2 (SCAP2) has been shown to bind to SIRP alpha. Evidence from immunoprecipitation experiments performed in COS-7 lysates suggests that the SH3 domain of SCAP2 is involved in the interaction.

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Compartment cytosol , plasma membrane
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Literature References
pubMedId Title Journal Year
10469599 SHPS-1 is a scaffold for assembling distinct adhesion-regulated multi-protein complexes in macrophages Curr Biol 1999