Reactome: A Curated Pathway Database

FPRL1 receptor binds a wide range of ligands (R-HSA-391913) [Homo sapiens]


FPRL1 has been reported to respond to numerous ligand with a broad range of structural diversity. It was originally identified as a low-affinity receptor for fMLF, but has greater affinity for many ligands including lipoxin A4, annexin-1, the truncated chemokine sCKbeta8-1 and humanin.

Additional Information
Compartment extracellular region , plasma membrane
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Literature References
pubMedId Title Journal Year
1374236 Isolation of a cDNA that encodes a novel granulocyte N-formyl peptide receptor Biochem Biophys Res Commun 1992