Reactome: A Curated Pathway Database

G-protein beta:gamma signalling

Stable Identifier
R-HSA-397795
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The classical role of the G-protein beta/gamma dimer was believed to be the inactivation of the alpha subunit, Gbeta/gamma was viewed as a negative regulator of Galpha signalling. It is now known that Gbeta/gamma subunits can directly modulate many effectors, including some also regulated by G alpha.

Literature References
PubMed ID Title Journal Year
Participants
Participant Of
Orthologous Events