Reactome: A Curated Pathway Database

p-S141,T402-PAK2

Stable Identifier
R-HSA-399824
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
PAK2
Chain
initiator methionine:1, chain:2-524, chain:2-212, chain:213-524
Reference Genes
Reference Transcript
Other Identifiers
 0003830148  11739268_s_at  11739269_s_at  11739270_at  11739271_s_at
 11739272_x_at  11739273_at  11739274_s_at  11739275_x_at  1245_i_at
 1559052_s_at  1560_g_at  16950017  208875_s_at  208876_s_at
 208877_3p_at  208877_at  208878_s_at  2659578  2659584
 2659585  2659586  2659587  2659588  2659589
 2659591  2659593  2659594  2659597  2659600
 2659601  2659602  2659603  2659604  2659605
 2659606  2659607  2659608  2659609  2659610
 2659611  2659612  2659613  2659614  34329_at
 3612676  3612683  3612686  3612689  3612690
 3612691  3612693  3PCS  5062  55663_at
 7794  8084963  A_14_P125078  A_23_P327307  A_32_P104075
 A_33_P3220833  AAA65442  AAA75468  AAH69613  BC069613
 CAB007794  CCDS3321  ENSG00000180370  ENSP00000314067  ENST00000327134
 EntrezGene:5062  g5138913_3p_a_at  GE59022  GO:0000166  GO:0002223
 GO:0002376  GO:0003674  GO:0003824  GO:0004672  GO:0004674
 GO:0004702  GO:0004871  GO:0005515  GO:0005524  GO:0005575
 GO:0005622  GO:0005623  GO:0005634  GO:0005737  GO:0005829
 GO:0005886  GO:0006464  GO:0006468  GO:0006469  GO:0006915
 GO:0006950  GO:0007155  GO:0007165  GO:0008150  GO:0008152
 GO:0008219  GO:0016020  GO:0016032  GO:0016301  GO:0016310
 GO:0016740  GO:0018105  GO:0019899  GO:0019901  GO:0023014
 GO:0030154  GO:0030234  GO:0030296  GO:0031267  GO:0031295
 GO:0038095  GO:0040007  GO:0040008  GO:0042802  GO:0043066
 GO:0043167  GO:0043226  GO:0044403  GO:0045296  GO:0046777
 GO:0048010  GO:0048365  GO:0048471  GO:0048856  GO:0050690
 GO:0050731  GO:0050852  GO:0060996  GO:0061098  GO:0071407
 GO:2001238  GO:2001271  HGNC:8591  Hs.284275.0.S1_3p_a_at  Hs.284275.0.S2_3p_a_at
 Hs.284275.0.S4_3p_at  Hs.284275.0.S4_3p_s_at  Hs.284275.0.S4_3p_x_at  Hs.518530  Hs.56974.0.A1_3p_s_at
 Hs2.56974.1.S1_3p_s_at  ILMN_1676385  ILMN_1712687  ILMN_1743106  IPR000095
 IPR000719  IPR008271  IPR011009  IPR017441  MIM:605022
 NM_002577  NP_002568  PAK2  PAK2-201  PF00069
 PF00786  PH_hs_0014731  SM00220  SM00285  TC03001100.hg
 U24153  U25975  U25975_at  uc003fwy.4  UPI0000141B02
 XM_011512870  XM_017006501  XP_011511172  XP_016861990
Participant Of
Other forms of this molecule
Inferred To
Modified Residues
Name Coordinate Modification PsiMod
O-phospho-L-threonine at 402 402
O-phospho-L-threonine [MOD:00047] A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
O-phospho-L-serine at 141 141
O-phospho-L-serine [MOD:00046] A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
UCSC human
ZINC - World Drugs
ZINC - FDA approved
GeneCards
ZINC - Substances
DOCK Blaster
ZINC target
PRO
ZINC - Predictions - Purchasable
HMDB Protein
PDB
Interactors
Confidence Score Interactor Accession Interactor Name Evidence (IntAct)
0.78 P63000 RAC1_HUMAN 4
0.775 O60504 VINEX_HUMAN 6
0.749 P60953 CDC42_HUMAN 5
0.696 Q9H4E5 RHOJ_HUMAN 5
0.688 Q14155 ARHG7_HUMAN 4
0.683 Q15052 ARHG6_HUMAN 4
0.669 Q9Y2X7 GIT1_HUMAN 3
0.655 O55043 ARHG7_RAT 8
0.619 P55210 CASP7_HUMAN 6
0.602 Q13177 PAK2_HUMAN 3
0.564 Q14161 GIT2_HUMAN 2
0.558 P53667 LIMK1_HUMAN 2
0.558 P04049 RAF1_HUMAN 2
0.524 P08631 HCK_HUMAN 2
0.524 Q8TEJ3 SH3R3_HUMAN 2
0.524 P62993 GRB2_HUMAN 2
0.524 P16333 NCK1_HUMAN 2
0.524 P12931 SRC_HUMAN 2
0.524 O94875 SRBS2_HUMAN 2
0.524 Q9BX66 SRBS1_HUMAN 2
0.488 Q9NYB9-2 ABI2 2
0.488 O43639 NCK2_HUMAN 2