Reactome: A Curated Pathway Database
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Collagen type II binds integrin alpha2beta1, alpha1beta1, alpha11beta1

Stable Identifier
R-HSA-4084910
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The widely-expressed collagen receptors integrin alpha2beta1 and alpha1beta1 both bind collagen types I-IV (Tulla et al. 2001). Integrin alpha1beta1 binds to collagen type IV and VI with higher affinity than to types I-III, whereas alpha2beta1 has a higher affinity for collagen types I-III than for type IV (Tulla et al. 2001).

Participants
Participant Of
Inferred From