Reactome: A Curated Pathway Database

Collagen type II binds integrin alpha2beta1, alpha1beta1, alpha11beta1 (R-HSA-4084910) [Homo sapiens]


The widely-expressed collagen receptors integrin alpha2beta1 and alpha1beta1 both bind collagen types I-IV (Tulla et al. 2001). Integrin alpha1beta1 binds to collagen type IV and VI with higher affinity than to types I-III, whereas alpha2beta1 has a higher affinity for collagen types I-III than for type IV (Tulla et al. 2001).

Additional Information
Compartment extracellular region , plasma membrane