Reactome: A Curated Pathway Database

Nucleotide-like (purinergic) receptors

Stable Identifier
R-HSA-418038
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

Purinergic receptors (Burnstock G, 2006; Abbracchio MP et al, 2009) are a family of newly characterized plasma membrane molecules involved in several cellular functions such as vascular reactivity, apoptosis and cytokine secretion. The functions of these receptors are as yet only partially characterized. The family includes the GPCR P2Y purinergic receptors and adenosine P1 receptors. A third family member, the P2X receptor, is a ligand-gated ion channel.

Literature References
PubMed ID Title Journal Year
19008000 Purinergic signalling in the nervous system: an overview Trends Neurosci 2009
16805422 Purinergic signalling--an overview Novartis Found Symp 2006
Participants
Participant Of
Orthologous Events