Butyrylcholinesterase and Platelet-activating factor acetylhydrolase hydrolyze acyl Ghrelin
Species Homo sapiens
The majority of circulating ghrelin is not acylated (des-acyl ghrelin). Acyl ghrelin can be deacylated in the bloodstream by butyrylcholinesterase and platelet-activating factor acetylhydrolase, which are associated with circulating lipids. Other enzymes may also have this capability. It is unknown if a portion of des-acyl ghrelin in the bloodstream is generated by direct synthesis and secretion.
Locations in the PathwayBrowser
Metabolism of proteins(Homo sapiens)