Reactome: A Curated Pathway Database

SLC9A6,7 exchange Na+ for H+ across the early endosome membrane

Stable Identifier
R-HSA-425983
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
Na+/H+ exchanger transport (at early endosome membrane)
Locations in the PathwayBrowser
Summation

NHE6 (SLC9A6) (Brett CL et al, 2002; Nakamura N et al, 2005) is expressed ubiquitously and thought to play a housekeeping role in pH homeostasis in early endosomes.

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
sodium:proton antiporter activity of SLC9A6,7 [early endosome membrane] SLC9A6,7 [early endosome membrane] sodium:proton antiporter activity (0015385)
Orthologous Events