Reactome: A Curated Pathway Database

Transcription of intergenic spacer of the rRNA gene (R-HSA-427366) [Homo sapiens]


As inferred from mouse cell models, intergenic spacer regions (IGS) located between rRNA transcription units contain upstream promoters and are transcribed by RNA Polymerase I. The IGS transcripts originate approximately 2 Kb upstream of the start of rRNA transcription and proceed though the main promoter of the rRNA gene.

Additional Information
Compartment nucleoplasm
Components of this entry
Input entries
Output entries
Catalyst Activity
PhysicalEntity Activity Active Units
RNA Polymerase I promoter escape complex DNA-directed RNA polymerase activity (0003899)