Reactome: A Curated Pathway Database

Transcription of intergenic spacer of the rRNA gene (R-HSA-427366)

Species Homo sapiens


As inferred from mouse cell models, intergenic spacer regions (IGS) located between rRNA transcription units contain upstream promoters and are transcribed by RNA Polymerase I. The IGS transcripts originate approximately 2 Kb upstream of the start of rRNA transcription and proceed though the main promoter of the rRNA gene.

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Additional Information
Compartment nucleoplasm
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Output entries
Catalyst Activity
PhysicalEntity Activity Active Units
RNA Polymerase I promoter escape complex DNA-directed RNA polymerase activity (0003899)