Reactome: A Curated Pathway Database
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Transcription of intergenic spacer of the rRNA gene

Stable Identifier
R-HSA-427366
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

As inferred from mouse cell models, intergenic spacer regions (IGS) located between rRNA transcription units contain upstream promoters and are transcribed by RNA Polymerase I. The IGS transcripts originate approximately 2 Kb upstream of the start of rRNA transcription and proceed though the main promoter of the rRNA gene.

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
DNA-directed RNA polymerase activity of RNA Polymerase I promoter escape complex [nucleoplasm] RNA Polymerase I promoter escape complex [nucleoplasm] DNA-directed RNA polymerase activity (0003899)
Inferred From