Transcription of intergenic spacer of the rRNA gene

Stable Identifier
R-HSA-427366
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

As inferred from mouse cell models, intergenic spacer regions (IGS) located between rRNA transcription units contain upstream promoters and are transcribed by RNA Polymerase I. The IGS transcripts originate approximately 2 Kb upstream of the start of rRNA transcription and proceed though the main promoter of the rRNA gene.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
DNA-directed 5'-3' RNA polymerase activity of RNA Polymerase I promoter escape complex [nucleoplasm]
Physical Entity
Activity
Inferred From