Reactome: A Curated Pathway Database

Recruitment of Profilin by Ena/Vasp proteins

Stable Identifier
R-HSA-428534
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Ena/VASP proteins enhance actin filament elongation via the recruitment of profilin:actin complexes to the tips of spreading lamellipodia. Profilin binds to the central proline rich domain of Ena/VASP protein.

Literature References
Participants
Participant Of
Orthologous Events