Reactome: A Curated Pathway Database

Activation of Rac

Stable Identifier
R-HSA-428540
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

A low level of Rac activity is essential to maintain axon outgrowth and Robo activation recruits Sos, a dual specificity GEF to the plasma membrane via Dock to activate Rac during midline repulsion.

Participants
Participant Of
Orthologous Events