Reactome: A Curated Pathway Database

NCK recruits WASP

Stable Identifier
R-HSA-430180
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The second SH3 domain of NCK interacts with the carboxy-terminal SH3 domain of WASP. WASP family proteins bind the Arp2/3 complex, stimulating its ability to nucleate actin filaments and induce filament branching.

Literature References
Participants
Participant Of
Orthologous Events