Reactome: A Curated Pathway Database

p-SLP-76:ADAP binds Ena/VASP (R-MMU-430200) [Mus musculus]


ADAP (FYB) is an adaptor protein containing multiple binding motifs including an enabled protein vasodilator-stimulated phosphoprotein homology domain 1 (EVH1)-binding domain. This domain binds Ena-VASP family proteins that regulate actin dynamics. The Ena-VASP family member EVL is found in regions of dynamic actin polymerization, such as F-actin rich patches and the distal tips of microspikes.

Additional Information
Compartment cytosol