Ca2+ influx into the post-synaptic cell

Stable Identifier
R-HSA-432164
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

NMDA receptors are activated upon binding of two ligands, glutamate and glycine.
The activation leads to Ca2+ influx into the post-synaptic cell. The local rise in the Ca2+ ion concentration further leads to activation of several Ca2+ dependent pathways leading to long term changes in the synapse.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
excitatory extracellular ligand-gated ion channel activity of NMDA receptor ligand complex [plasma membrane]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea