Reactome: A Curated Pathway Database
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Activation of NMDA receptor

Stable Identifier
R-HSA-432172
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

NMDA receptors require binding of two ligands; the agonist, glutamate and co-agonist, glycine. The N terminal extracellular ligand binding domain in NR1 subunits binds co-agonist glycine and the N terminal extracellular ligand binding domain in NR2 binds glutamate.

Literature References
Participants
Participant Of
Orthologous Events