Reactome: A Curated Pathway Database

PDK1 binds PKC zeta (R-HSA-437192) [Homo sapiens]


3-phosphoinositide dependent protein kinase-1 (PDK1) and Protein kinase C zeta type (PKC zeta) are associated in fibroblasts. PDK1, also known as Protein kinase B kinase (PKBK), is known to co-localise with Protein kinase B (PKB) in transfected fibroblasts and platelets, suggesting a complex of PDK1, PKB and PKC zeta.

Additional Information
Compartment cytosol , plasma membrane
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Literature References
pubMedId Title Journal Year
9768361 Regulation of protein kinase C zeta by PI 3-kinase and PDK-1 Curr Biol 1998
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