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Ras activation

Stable Identifier
R-HSA-442732
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Binding of RasGRF to Ca2+/Calmodulin in the presence of high Ca2+ leads to the activation of Ras. Activation of Ras involves the exchange of GDP for GTP.

Literature References
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
Ras guanyl-nucleotide exchange factor activity of RasGRF:Ca/calmodulin [plasma membrane]
Physical Entity
Activity
Orthologous Events