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CaMKII enters cytoplasm

Stable Identifier
R-HSA-445367
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

CaMKII gets activated upon Ca2+ influx through the NMDA receptor and moves from plasma membrane to cytoplasm and then nucleus where it phosphorylates CREB at serine 133.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
excitatory extracellular ligand-gated ion channel activity of NMDA receptor ligand complex [plasma membrane]
Physical Entity
Activity
Orthologous Events