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ATP Hydrolysis By Myosin

Stable Identifier
R-HSA-445699
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Once ATP is bound, myosin, which is an ATPase, uses the energy from the cleavage of the terminal phosphate to pivot the myosin head back, away from the actin filamentous chain. This change in conformation "resets" the myosin molecule, leaving it ready to bind the actin filament once more and slide the myosin filament along the actin filament, continuing the contractile cycle.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
myosin phosphatase activity of ATP Bound Smooth Muscle Myosin Complex [cytosol]
Physical Entity
Activity
Orthologous Events