Reactome: A Curated Pathway Database
The EBI data centre will be shutting down from the afternoon (BST) of Friday 26th August until the afternoon of Tuesday 30th August 2016 for essential maintenance. This might have an impact on some Reactome services and we apologize for any inconvenience.

ATP Hydrolysis By Myosin

Stable Identifier
Homo sapiens
Locations in the PathwayBrowser

Once ATP is bound, myosin, which is an ATPase, uses the energy from the cleavage of the terminal phosphate to pivot the myosin head back, away from the actin filamentous chain. This change in conformation "resets" the myosin molecule, leaving it ready to bind the actin filament once more and slide the myosin filament along the actin filament, continuing the contractile cycle.

Literature References
Participant Of
This entity is regulated by:
Title Physical Entity Activity
myosin phosphatase activity of ATP Bound Smooth Muscle Myosin Complex [cytosol] ATP Bound Smooth Muscle Myosin Complex [cytosol] myosin phosphatase activity (0017018)
Orthologous Events