Reactome: A Curated Pathway Database

IL6 (R-HSA-447100) [Homo sapiens]

Reference Gene Product
Locations in the PathwayBrowser
Additional Information
External reference name IL6
External reference id P05231
Synonyms Interleukin-6
Compartment extracellular region
Other Identifiers
 0000870048  11746463_a_at  1ALU  1IL6  1N2Q
 1P9M  205207_at  2IL6  3569  38299_at
 4CNI  4J4L  4NI7  4NI9  4O9H
 A_23_P71037  AAA52728  AAA52729  AAA59154  AAC41704
 AAD13886  AAH15511  AAK48987  AAS07539  AAV38553
 AAV38554  AC073072  AF372214  B4DNV3  BC015511
 BT019748  BT019749  CAA27990  CAA27991  CAA28026
 CAA28268  CAA68278  CAB023406  CAG29292  CCDS5375
 CH236948  CH471073  CR450296  EAL24265  EAW93756
 EAW93758  ENSG00000136244  ENSP00000258743  ENSP00000385675  ENST00000258743
 ENST00000404625  EntrezGene:3569  g10834983_3p_at  GE59660  HGNC:6018
 IL6  IL6-001  IL6-201  ILMN_1699651  IPR003574
 IPR009079  IPR030473  IPR030474  M14584  M18403
 M29150  M54894  MIM:147620  NM_000600  NP_000591
 OTTHUMP00000158544  PF00489  PH_hs_0026738  PR00433  PR00434
 Q75MH2  R-HSA-1059683  R-HSA-110056  R-HSA-112409  R-HSA-112411
 R-HSA-1280215  R-HSA-162582  R-HSA-168256  R-HSA-2262752  R-HSA-2559582
 R-HSA-2559583  R-HSA-449147  R-HSA-5683057  R-HSA-5684996  S56892
 SM00126  uc003svj.5  uc064bxs.1  UPI000002C4A6  X04402
 X04403  X04430  X04602  X04602_s_at  XM_011515390
 XP_011513692  Y00081  Y00081_s_at
Secondary Identifiers IL6_HUMAN, Q9UCU2, Q9UCU3, Q9UCU4
Gene Names IL6, IFNB2
Chain signal peptide:1-29, chain:30-212
Reference Genes
Database Identifier
dbSNP Gene 3569
CTD Gene 3569
BioGPS Gene 3569
NCBI Gene 3569
ENSEMBL ENSG00000136244
KEGG Gene IL6
Orphanet 16791
Reference Transcripts
Database Identifier
RefSeq NM_000600
Cross References
Database Identifier
RefSeq NP_000591
DOCK Blaster 4O9H, 4NI7, 4NI9, 4CNI, 4J4L, 1IL6, 2IL6, 1ALU, 1P9M, 1N2Q
HMDB_protein HMDBP02087
PRO P05231
GeneCards P05231
UCSC human P05231
Protein Data Bank 4O9H, 4NI7, 4NI9, 4CNI, 4J4L, 1IL6, 2IL6, 1ALU, 1P9M, 1N2Q
Interactions
Confidence Score Interactor Accession Interactor Name Evidence
0.697 P08887 IL6RA_HUMAN 5
0.573 Q05516 ZBT16_HUMAN 2