Reactome: A Curated Pathway Database

IL6 (R-HSA-447100)

Species Homo sapiens

Locations in the PathwayBrowser
Cellular responses to stress(Homo sapiens)
Immune System(Homo sapiens)

Signal Transduction(Homo sapiens)

Additional Information
External reference name IL6
External reference id P05231
Synonyms Interleukin-6
Compartment extracellular region
Other Identifiers 0000870048, 11746463_a_at, 1ALU, 1IL6, 1N2Q, 1P9M, 205207_at, 2IL6, 3569, 38299_at, 4CNI, 4J4L, 4NI7, 4NI9, 4O9H, A_23_P71037, AAA52728, AAA52729, AAA59154, AAC41704, AAD13886, AAH15511, AAK48987, AAS07539, AAV38553, AAV38554, AC073072, AF372214, BC015511, BT019748, BT019749, CAA27990, CAA27991, CAA28026, CAA28268, CAA68278, CAB023406, CAG29292, CCDS5375, CH236948, CH471073, CR450296, EAL24265, EAW93756, EAW93758, ENSG00000136244, ENSP00000258743, ENSP00000385675, ENST00000258743, ENST00000404625, EntrezGene:3569, g10834983_3p_at, GE59660, HGNC:6018, IL6, IL6-001, IL6-201, ILMN_1699651, IPR003574, IPR009079, IPR030473, IPR030474, M14584, M18403, M29150, M54894, MIM:147620, MIM:148000, MIM:604302, NM_000600, NP_000591, OTTHUMP00000158544, PF00489, PH_hs_0026738, PR00433, PR00434, Q75MH2, R-HSA-1059683, R-HSA-110056, R-HSA-112409, R-HSA-112411, R-HSA-1280215, R-HSA-162582, R-HSA-168256, R-HSA-2262752, R-HSA-2559582, R-HSA-2559583, R-HSA-449147, R-HSA-5683057, R-HSA-5684996, S56892, SM00126, uc003svj.5, uc064bxs.1, UPI000002C4A6, X04402, X04403, X04430, X04602, X04602_s_at, XP_011513692, Y00081, Y00081_s_at
Secondary Identifiers IL6_HUMAN, Q9UCU2, Q9UCU3, Q9UCU4
Gene Names IL6, IFNB2
Chain signal peptide:1-29, chain:30-212
Reference Genes
Database Identifier
dbSNP Gene 3569
CTD Gene 3569
BioGPS Gene 3569
NCBI Gene 3569
ENSEMBL ENSG00000136244
KEGG Gene 3569
Orphanet 16791
Reference Transcripts
Database Identifier
RefSeq NM_000600
Cross References
Database Identifier
RefSeq NP_000591
DOCK Blaster 1N2Q, 1P9M, 1ALU, 1IL6, 2IL6, 4CNI, 4J4L, 4NI7, 4NI9, 4O9H
HMDB_protein HMDBP02087
PRO P05231
GeneCards P05231
UCSC human P05231
Protein Data Bank 1N2Q, 1P9M, 1ALU, 1IL6, 2IL6, 4CNI, 4J4L, 4NI7, 4NI9, 4O9H