Reactome: A Curated Pathway Database

p-T221,Y223-MAPK10 (R-HSA-450311)

Species Homo sapiens

Locations in the PathwayBrowser
Cellular responses to stress(Homo sapiens)
Immune System(Homo sapiens)

Other forms of this molecule

Additional Information
External reference name MAPK10
External reference id P53779
Synonyms p-T221,Y223-JNK3
Compartment nucleoplasm
Other Identifiers 0000940497, 0001980692, 0004480059, 0004850128, 0100780619, 11730066_s_at, 11741019_a_at, 1708_at, 1709_g_at, 1JNK, 1PMN, 1PMU, 1PMV, 204813_at, 237413_at, 2B1P, 2EXC, 2O0U, 2O2U, 2OK1, 2P33, 2R9S, 2WAJ, 2ZDT, 2ZDU, 3CGF, 3DA6, 3FI2, 3FI3, 3FV8, 3G90, 3G9L, 3G9N, 3KVX, 3OXI, 3OY1, 3PTG, 3RTP, 3TTI, 3TTJ, 3V6R, 3V6S, 45430_at, 4H36, 4H39, 4H3B, 4KKE, 4KKG, 4KKH, 4U79, 4W4V, 4W4W, 4W4X, 4W4Y, 4WHZ, 4Y46, 4Y5H, 4Z9L, 5602, 69092_at, A_23_P45025, A_33_P3254216, AAC50101, AAC50604, AAC50605, AAH35057, AC096953, AC104059, AC104827, AC108054, AC110076, AK057723, AK124791, BAG51956, BAG54096, BC035057, CAB022625, CCDS34026, CCDS3612, CCDS3613, CCDS43247, CH471057, EAX05963, ENSG00000109339, ENSP00000352157, ENSP00000355297, ENSP00000378589, ENSP00000378595, ENSP00000378598, ENST00000359221, ENST00000361569, ENST00000395160, ENST00000395166, ENST00000395169, EntrezGene:5602, g4506080_3p_at, GE54461, GE62730, HGNC:6872, Hs.125503, Hs.25209.0.A1_3p_at, Hs.666725, Hs.739136, ILMN_1748281, ILMN_1766904, ILMN_1815780, ILMN_2256907, ILMN_2340131, IPR000719, IPR002290, IPR003527, IPR008271, IPR008351, IPR011009, MAPK10, MAPK10-001, MAPK10-002, MAPK10-004, MAPK10-005, MAPK10-012, MIM:602897, NM_002753, NM_138980, NM_138981, NM_138982, NP_002744, NP_620446, NP_620447, NP_620448, OTTHUMP00000161179, OTTHUMP00000161180, OTTHUMP00000161182, OTTHUMP00000161183, OTTHUMP00000218566, PF00069, PH_hs_0031094, PR01772, R-HSA-166016, R-HSA-166054, R-HSA-166058, R-HSA-166166, R-HSA-168138, R-HSA-168142, R-HSA-168164, R-HSA-168176, R-HSA-168179, R-HSA-168181, R-HSA-168188, R-HSA-168249, R-HSA-168256, R-HSA-168898, R-HSA-181438, R-HSA-2262752, R-HSA-2454202, R-HSA-2559580, R-HSA-2559583, R-HSA-2871796, R-HSA-450282, R-HSA-450294, R-HSA-450321, R-HSA-450341, R-HSA-937061, R-HSA-975138, R-HSA-975155, R-HSA-975871, SM00220, U07620, U07620_at, U34819, U34820, uc003hpp.4, uc003hpr.4, uc003hps.4, uc003hpt.4, uc010ikg.4, UPI000002AE11, UPI00000336D5, UPI0000049042, UPI00001612A1, XM_005263129, XM_005263130, XM_005263135, XM_011532117, XM_011532118, XP_005263186, XP_005263187, XP_005263188, XP_005263192, XP_006714331, XP_006714332, XP_011530419, XP_011530420, XP_011530422, XP_011530423
Secondary Identifiers MK10_HUMAN, A6NFS3, A6NG28, B3KQ94, Q15707, Q49AP1
Gene Names MAPK10, JNK3, JNK3A, PRKM10, SAPK1B
Chain chain:1-464
This entry is a component of:
hasMember
Reference Genes
Database Identifier
dbSNP Gene 5602
CTD Gene 5602
BioGPS Gene 5602
NCBI Gene 5602
ENSEMBL ENSG00000109339
KEGG Gene 5602
Orphanet 19563
Reference Transcripts
Database Identifier
RefSeq NM_138980
Cross References
Database Identifier
RefSeq NP_620446, NP_620448, NP_002744, NP_620447
ZINC_target P53779
DOCK Blaster 1PMU, 1PMV, 2B1P, 2EXC, 2O0U, 2O2U, 2OK1, 2P33, 2R9S, 2WAJ, 2ZDT, 2ZDU, 3CGF, 3DA6, 3FI2, 3FI3, 3FV8, 3G90, 3G9L, 3G9N, 3KVX, 3OY1, 3RTP, 3TTI, 3TTJ, 3V6R, 3V6S, 4KKE, 4KKG, 4KKH, 4U79, 4W4V, 4W4W, 4W4X, 4W4Y, 4WHZ, 4Y46, 4Y5H, 4Z9L, 1JNK, 1PMN, 3OXI, 3PTG, 4H39, 4H36, 4H3B
HMDB_protein HMDBP01533
PRO P53779
GeneCards P53779
UCSC human P53779
Protein Data Bank 1PMU, 1PMV, 2B1P, 2EXC, 2O0U, 2O2U, 2OK1, 2P33, 2R9S, 2WAJ, 2ZDT, 2ZDU, 3CGF, 3DA6, 3FI2, 3FI3, 3FV8, 3G90, 3G9L, 3G9N, 3KVX, 3OY1, 3RTP, 3TTI, 3TTJ, 3V6R, 3V6S, 4KKE, 4KKG, 4KKH, 4U79, 4W4V, 4W4W, 4W4X, 4W4Y, 4WHZ, 4Y46, 4Y5H, 4Z9L, 1JNK, 1PMN, 3OXI, 3PTG, 4H39, 4H36, 4H3B
ModifiedResidues
Name Coordinate Modification PsiMod Name PsiMod Identifier PsiMod Definition
O-phospho-L-threonine at 221 221 O-phospho-L-threonine 00047 A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
O4'-phospho-L-tyrosine at 223 223 O4'-phospho-L-tyrosine 00048 A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Inferred Entries
Inferred to