Reactome: A Curated Pathway Database
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Regulation of mRNA stability by proteins that bind AU-rich elements

Stable Identifier
R-HSA-450531
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

RNA elements rich in adenine and uracil residues (AU-rich elements) bind specific proteins which either target the RNA for degradation or, more rarely, stabilize the RNA. The activity of the AU-element binding proteins is regulated, usually by phosphorylation but also by subcellular localization.

Literature References
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