Reactome: A Curated Pathway Database

Activation of Ca-permeable Kainate receptors (R-HSA-451311) [Homo sapiens]

Reaction
Summation

Kainate receptors that are assembled with subunits GRIK1-5, are Ca2+ permeable if GRIK1 and GRIK2 are not edited at the Q/R or other sites.
These channels permit Ca2+ upon activation by glutamate or other agonists.

Additional Information
Compartment cytosol , extracellular region , plasma membrane
Catalyst Activity
PhysicalEntity Activity Active Units
kaiante Receptors ligand-gated ion channel activity (0015276)