Reactome: A Curated Pathway Database

Activation of Ca-permeable Kainate receptors

Stable Identifier
R-HSA-451311
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Kainate receptors that are assembled with subunits GRIK1-5, are Ca2+ permeable if GRIK1 and GRIK2 are not edited at the Q/R or other sites.
These channels permit Ca2+ upon activation by glutamate or other agonists.

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
ligand-gated ion channel activity of kaiante Receptors [plasma membrane] kaiante Receptors [plasma membrane] ligand-gated ion channel activity (0015276)
Orthologous Events