Reactome: A Curated Pathway Database

Exocytosis of platelet alpha granule contents

Stable Identifier
R-HSA-481007
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Alpha granules contain mainly polypeptides such as fibrinogen, von Willebrand factor, growth factors and protease inhibitors that supplement thrombin generation at the site of injury. In addtion to their role in hemostasis, platelets also contain angiogenesis stimulators and inhibitors (Italiano et al. 2008).

Literature References
Participants
Participant Of
Orthologous Events