Reactome: A Curated Pathway Database

Exocytosis of platelet alpha granule contents (R-HSA-481007)

Species Homo sapiens

Summation

Alpha granules contain mainly polypeptides such as fibrinogen, von Willebrand factor, growth factors and protease inhibitors that supplement thrombin generation at the site of injury. In addtion to their role in hemostasis, platelets also contain angiogenesis stimulators and inhibitors (Italiano et al. 2008).

Locations in the PathwayBrowser
Additional Information
Compartment plasma membrane