Reactome: A Curated Pathway Database

Chromatin organization (R-HSA-4839726) [Homo sapiens]


Chromatin organization refers to the composition and conformation of complexes between DNA, protein and RNA. It is determined by processes that result in the specification, formation or maintenance of the physical structure of eukaryotic chromatin. These processes include histone modification, DNA modification, and transcription. The modifications are bound by specific proteins that alter the conformation of chromatin.

Locations in the PathwayBrowser
Additional Information
Compartment nucleoplasm
GO Biological Process chromatin organization (0006325)
Literature References
pubMedId Title Journal Year
21342762 Chromatin higher-order structures and gene regulation Curr. Opin. Genet. Dev. 2011
15598472 Chromatin organization in the mammalian nucleus Int. Rev. Cytol. 2005