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p-STAT5A, p-STAT5B [cytosol]
Stable Identifier
R-HSA-507929
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
cytosol
Synonyms
p-STAT5
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
FLT3 signaling in disease (Homo sapiens)
Signaling by FLT3 ITD and TKD mutants (Homo sapiens)
STAT5 activation downstream of FLT3 ITD mutants (Homo sapiens)
FLT3 ITD mutants phosphorylate STAT5 (Homo sapiens)
p-6Y FLT3 ITD mutant dimers:GRB2:p-Y GAB2:PTPN11:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
PTPN11:p-STAT5 dissociates from mutant FLT3 (Homo sapiens)
PTPN11:p-STAT5 [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-6Y FLT3 ITD mutant dimers:GRB2:p-Y GAB2:PTPN11:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
PTPN11:p-STAT5 translocates to nucleus downstream of mutant FLT3 (Homo sapiens)
PTPN11:p-STAT5 [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5 dissociates from mutant FLT3 (Homo sapiens)
p-6Y FLT3 ITD mutant dimers:GRB2:p-Y GAB2:PTPN11:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5 translocates to nucleus downstream of mutant FLT3 (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
Signaling by FLT3 fusion proteins (Homo sapiens)
FLT3 fusions activate STAT5 (Homo sapiens)
p-Y FLT3 fusions:p-STAT5 [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5 dissociates from FLT3 fusion proteinsp- (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y FLT3 fusions:p-STAT5 [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5 translocates to nucleus downstream of mutant FLT3 (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
Signaling by FGFR in disease (Homo sapiens)
Signaling by FGFR1 in disease (Homo sapiens)
FGFR1 mutant receptor activation (Homo sapiens)
Signaling by cytosolic FGFR1 fusion mutants (Homo sapiens)
Phosphorylation of STAT5 by cytosolic FGFR1 fusions (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
FLT3 Signaling (Homo sapiens)
STAT5 Activation (Homo sapiens)
Activator phosphorylates STAT5 (Homo sapiens)
Activators of STAT5:p-STAT5 [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5 dissociates from activator:STAT5 complex (Homo sapiens)
Activators of STAT5:p-STAT5 [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
Growth hormone receptor signaling (Homo sapiens)
STAT5 dimers translocate to the nucleus (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
STAT5 tyrosine phosphorylation (Homo sapiens)
Growth Hormone:Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5 dimerizes (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5A/B dissociates from the Growth Hormone receptor (Homo sapiens)
Growth Hormone:Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
Prolactin receptor signaling (Homo sapiens)
PRLR-bound STAT5 is phosphorylated (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
Signaling by CSF3 (G-CSF) (Homo sapiens)
p-Y-STAT1,3,5 dimer translocates from the cytosol to the nucleoplasm (Homo sapiens)
p-Y-STAT1,3,5 dimer [cytosol] (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y-STAT1,3,5 dimerize (Homo sapiens)
p-Y-STAT1,3,5 dimer [cytosol] (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-2 family signaling (Homo sapiens)
Interleukin-2 signaling (Homo sapiens)
Phosphorylated STAT5 is released (Homo sapiens)
IL2:IL2R trimer p-(Y338,Y392, Y510) beta subunit:p-JAK1:JAK3:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
Recruited STAT5 is phosphorylated (Homo sapiens)
IL2:IL2R trimer p-(Y338,Y392, Y510) beta subunit:p-JAK1:JAK3:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
STAT5 dimers translocate to the nucleus (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5 dimerizes (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Homo sapiens)
Activation of STAT5a/b by JAK2 (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
High affinity IL-5 receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
IL3:IL3R active complex, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
STAT5 dimers translocate to the nucleus (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5 dimerizes (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5 dissociates from the receptor complex (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
High affinity IL-5 receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
IL3:IL3R active complex, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
Interleukin-7 signaling (Homo sapiens)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Homo sapiens)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
STAT5 dimers translocate to the nucleus (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5 dimerizes (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B dissociate from IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B (Homo sapiens)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Erythropoietin (Homo sapiens)
Erythropoietin activates STAT5 (Homo sapiens)
JAK2 and LYN phosphorylate STAT5 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 (Homo sapiens)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5 dissociates from EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 (Homo sapiens)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
Signaling by Leptin (Homo sapiens)
JAK2 Phosphorylates STAT5 in Response to Leptin (Homo sapiens)
LEP:p-LEPR:p-JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
Phosphorylated STAT5 Dissociates from Leptin Receptor (Homo sapiens)
LEP:p-LEPR:p-JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
STAT5 dimers translocate to the nucleus (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5 dimerizes (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
Participants
members
p-Y694-STAT5A [cytosol]
(Homo sapiens)
p-Y699-STAT5B [cytosol]
(Homo sapiens)
Participates
as an output of
Phosphorylated STAT5 Dissociates from Leptin Receptor (Homo sapiens)
p-STAT5A/B dissociates from the Growth Hormone receptor (Homo sapiens)
p-STAT5 dissociates from FLT3 fusion proteinsp- (Homo sapiens)
p-STAT5 dissociates from activator:STAT5 complex (Homo sapiens)
p-STAT5 dissociates from mutant FLT3 (Homo sapiens)
Phosphorylation of STAT5 by cytosolic FGFR1 fusions (Homo sapiens)
p-STAT5 dissociates from the receptor complex (Homo sapiens)
p-STAT5A, p-STAT5B dissociate from IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B (Homo sapiens)
p-STAT5 dissociates from EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 (Homo sapiens)
Phosphorylated STAT5 is released (Homo sapiens)
as a component of
LEP:p-LEPR:p-JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
Growth Hormone:Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:p-STAT5 [plasma membrane] (Homo sapiens)
p-Y FLT3 fusions:p-STAT5 [cytosol] (Homo sapiens)
PTPN11:p-STAT5 [cytosol] (Homo sapiens)
p-6Y FLT3 ITD mutant dimers:GRB2:p-Y GAB2:PTPN11:p-STAT5 [plasma membrane] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer:p-STAT5 [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B [plasma membrane] (Homo sapiens)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-STAT5 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,Y392, Y510) beta subunit:p-JAK1:JAK3:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
as a member of
Activators of STAT5:p-STAT5 [cytosol] (Homo sapiens)
as an input of
p-STAT5 translocates to nucleus downstream of mutant FLT3 (Homo sapiens)
p-STAT5 dimerizes (Homo sapiens)
Inferred To
p-STAT5A, p-STAT5B [cytosol]
(Bos taurus)
p-STAT5A, p-STAT5B [cytosol]
(Canis familiaris)
p-STAT5A, p-STAT5B [cytosol]
(Danio rerio)
p-STAT5A, p-STAT5B [cytosol]
(Gallus gallus)
p-STAT5A, p-STAT5B [cytosol]
(Mus musculus)
p-STAT5A, p-STAT5B [cytosol]
(Rattus norvegicus)
p-STAT5A, p-STAT5B [cytosol]
(Sus scrofa)
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