Reactome: A Curated Pathway Database

Organic cation transport (R-HSA-549127)

Species Homo sapiens


The organic cation transporters comprise three SLC22 members, OCT1-3. They can transport a wide range of organic cations including weak bases. All transport by OCTs is electrogenic, sodium-independent and bidirectional. Two further organic cation transporters mediate transport of ergothioneine and carnitine (Koepsell H and Endou H, 2004).

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Literature References
pubMedId Title Journal Year
12883891 The SLC22 drug transporter family Pflugers Arch 2004