Reactome: A Curated Pathway Database
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Organic cation transport

Stable Identifier
R-HSA-549127
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

The organic cation transporters comprise three SLC22 members, OCT1-3. They can transport a wide range of organic cations including weak bases. All transport by OCTs is electrogenic, sodium-independent and bidirectional. Two further organic cation transporters mediate transport of ergothioneine and carnitine (Koepsell H and Endou H, 2004).

Literature References
PubMed ID Title Journal Year
12883891 The SLC22 drug transporter family Pflugers Arch 2004
Participants
Participant Of
Orthologous Events