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LPIN2 [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-549165
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
lipin 2
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
Glycerophospholipid biosynthesis (Homo sapiens)
Synthesis of PC (Homo sapiens)
PA is dephosphorylated to DAG by LPIN (Homo sapiens)
LPIN [endoplasmic reticulum membrane] (Homo sapiens)
LPIN2:Mg2+ [endoplasmic reticulum membrane] (Homo sapiens)
LPIN2 [endoplasmic reticulum membrane] (Homo sapiens)
Synthesis of PE (Homo sapiens)
PA is dephosphorylated to DAG by LPIN (Homo sapiens)
LPIN [endoplasmic reticulum membrane] (Homo sapiens)
LPIN2:Mg2+ [endoplasmic reticulum membrane] (Homo sapiens)
LPIN2 [endoplasmic reticulum membrane] (Homo sapiens)
Triglyceride metabolism (Homo sapiens)
Triglyceride biosynthesis (Homo sapiens)
1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate (Homo sapiens)
LPIN1,2,3 [endoplasmic reticulum membrane] (Homo sapiens)
LPIN2 [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q92539 LPIN2
Gene Names
LPIN2, KIAA0249
Chain
chain:1-896
Reference Genes
BioGPS Gene:9663 LPIN2
COSMIC (genes):LPIN2 LPIN2
CTD Gene:9663 LPIN2
dbSNP Gene:9663 LPIN2
ENSEMBL:ENSG00000101577 LPIN2
ENSEMBL_homo_sapiens_GENE:ENSG00000101577.11 LPIN2
HGNC:14450 LPIN2
KEGG Gene (Homo sapiens):9663 LPIN2
Monarch:9663 LPIN2
NCBI Gene:9663 LPIN2
OMIM:605519 LPIN2
UCSC:Q92539 LPIN2
Reference Transcript
RefSeq:XM_005258178.3 LPIN2
RefSeq:XM_005258179.4 LPIN2
RefSeq:NM_014646.2 LPIN2
RefSeq:XM_017026098.1 LPIN2
RefSeq:XM_017026099.1 LPIN2
Other Identifiers
11744149_at
11744150_s_at
11744151_x_at
16853498
202459_PM_s_at
202459_s_at
202460_PM_s_at
202460_s_at
3796334
3796336
3796337
3796338
3796339
3796340
3796341
3796342
3796343
3796344
3796348
3796351
3796353
3796355
3796357
3796358
3796361
3796362
3796363
3796365
3796366
3796368
3796369
3796370
3796371
3796387
3796388
3796391
3796404
3796405
3796407
40447_at
8022022
9663
A_24_P301557
D87436_at
GE57393
GO:0003713
GO:0003824
GO:0005634
GO:0005737
GO:0005783
GO:0005789
GO:0005829
GO:0006351
GO:0006355
GO:0006629
GO:0006631
GO:0008195
GO:0009062
GO:0016020
GO:0016787
GO:0019432
GO:0032869
GO:0043226
GO:0045944
GO:0140110
HMNXSV003003377
HMNXSV003028614
Hs.166318.0.A1_3p_a_at
ILMN_1670028
ILMN_2133100
PH_hs_0025602
TC18000285.hg
TC18000803.hg
g7662021_3p_a_at
Participates
as a member of
LPIN1,2,3 [endoplasmic reticulum membrane] (Homo sapiens)
as a component of
LPIN2:Mg2+ [endoplasmic reticulum membrane] (Homo sapiens)
Other forms of this molecule
p-S106-LPIN2 [nucleoplasm]
LPIN2 [nuclear envelope]
Inferred To
lpin-1 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
LPIN2 [endoplasmic reticulum membrane]
(Bos taurus)
LPIN2 [endoplasmic reticulum membrane]
(Canis familiaris)
LPIN2 [endoplasmic reticulum membrane]
(Dictyostelium discoideum)
LPIN2 [endoplasmic reticulum membrane]
(Gallus gallus)
LPIN2 [endoplasmic reticulum membrane]
(Plasmodium falciparum)
LPIN2 [endoplasmic reticulum membrane]
(Sus scrofa)
PAH1 [endoplasmic reticulum membrane]
(Saccharomyces cerevisiae)
lpin2 [endoplasmic reticulum membrane]
(Xenopus tropicalis)
ned1 [endoplasmic reticulum membrane]
(Schizosaccharomyces pombe)
Lpin [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Lpin2 [endoplasmic reticulum membrane]
(Mus musculus)
Lpin2 [endoplasmic reticulum membrane]
(Rattus norvegicus)
Cross References
RefSeq
XP_005258235.1
,
XP_016881588.1
,
NP_055461.1
,
XP_016881587.1
,
XP_005258236.1
Guide to Pharmacology - Targets
1436
OpenTargets
ENSG00000101577
GeneCards
Q92539
HPA
ENSG00000101577-LPIN2
Ensembl
ENST00000697040
,
ENST00000261596
,
ENST00000677752
,
ENSG00000101577
,
ENSP00000261596
,
ENSP00000513062
,
ENSP00000504857
PRO
Q92539
Pharos - Targets
Q92539
Orphanet
16370
HMDB Protein
HMDBP11806
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