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SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane]
Stable Identifier
R-HSA-5607781
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Formation of Fibrin Clot (Clotting Cascade) (Homo sapiens)
Common Pathway of Fibrin Clot Formation (Homo sapiens)
Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. (Homo sapiens)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Homo sapiens)
factor V -> factor Va + factor V activation peptide (Homo sapiens)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Homo sapiens)
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Homo sapiens)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Homo sapiens)
Intrinsic Pathway of Fibrin Clot Formation (Homo sapiens)
factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer (Homo sapiens)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Homo sapiens)
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Homo sapiens)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Homo sapiens)
Participants
components
activated thrombin (factor IIa) [plasma membrane]
(Homo sapiens)
SERPINE2:GAG [plasma membrane]
(Homo sapiens)
Participates
as an output of
Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. (Homo sapiens)
This entity regulates
Negatively
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides
(Homo sapiens)
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst)
(Homo sapiens)
factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer
(Homo sapiens)
factor V -> factor Va + factor V activation peptide
(Homo sapiens)
Inferred To
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane]
(Bos taurus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane]
(Canis familiaris)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane]
(Gallus gallus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane]
(Mus musculus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane]
(Rattus norvegicus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane]
(Sus scrofa)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane]
(Xenopus tropicalis)
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