Reactome: A Curated Pathway Database

PRKAR1A (R-HSA-57836) [Homo sapiens]

Reference Gene Product
Locations in the PathwayBrowser
Other forms of this molecule
Additional Information
External reference name PRKAR1A
External reference id P10644
Synonyms cAMP-dependent protein kinase type I-alpha regulatory chain, Tissue- specific extinguisher-1
Compartment cytosol
Other Identifiers
 0001050072  11722007_a_at  11722008_a_at  11753791_s_at  200603_at
 200604_s_at  200605_s_at  226_at  227_g_at  41768_at
 54729_at  5573  60224_at  A_14_P136947  A_23_P433753
 A_24_P356592  AAB50921  AAB50922  AAH36285  AAH93042
 AC079210  AK097580  AK312307  B2R5T5  BAG35232
 BAG53489  BC036285  BC093042  CAA68925  CAB019378
 CCDS11678  CCDS62307  CH471099  EAW89060  EAW89061
 EAW89062  EAW89063  EAW89065  ENSG00000108946  ENSP00000351410
 ENSP00000376475  ENSP00000445625  ENSP00000464977  ENSP00000466459  ENSP00000468106
 ENST00000358598  ENST00000392711  ENST00000536854  ENST00000586397  ENST00000588188
 ENST00000589228  EntrezGene:5573  g1526988_3p_a_at  g4506062_3p_a_at  GE61216
 GE87724  HGNC:9388  HPA049847  HPA049979  Hs.183037.0.A3_3p_at
 Hs.280342  ILMN_1738632  ILMN_2277077  ILMN_2389590  IPR000595
 IPR003117  IPR012198  IPR018488  IPR018490  LRG_514
 LRG_514t1  LRG_514t2  M18468  M33336  M33336_at
 MIM:188830  NM_001276289  NM_001276290  NM_001278433  NM_002734
 NM_212471  NM_212472  NP_001263218  NP_001263219  NP_001265362
 NP_002725  NP_997636  NP_997637  OTTHUMP00000263402  OTTHUMP00000263405
 OTTHUMP00000263407  OTTHUMP00000263413  OTTHUMP00000263415  PF00027  PF02197
 PH_hs_0028092  PR00103  PRKAR1A  PRKAR1A-001  PRKAR1A-002
 PRKAR1A-004  PRKAR1A-005  PRKAR1A-006  PRKAR1A-201  R-HSA-109582
 R-HSA-111885  R-HSA-111931  R-HSA-111933  R-HSA-111996  R-HSA-111997
 R-HSA-112040  R-HSA-112043  R-HSA-1227986  R-HSA-1251932  R-HSA-1430728
 R-HSA-1489509  R-HSA-162582  R-HSA-163359  R-HSA-163615  R-HSA-163685
 R-HSA-164378  R-HSA-166520  R-HSA-167021  R-HSA-168249  R-HSA-168256
 R-HSA-177929  R-HSA-180024  R-HSA-186763  R-HSA-186797  R-HSA-187037
 R-HSA-190236  R-HSA-212718  R-HSA-2172127  R-HSA-2424491  R-HSA-372790
 R-HSA-381676  R-HSA-382551  R-HSA-422356  R-HSA-432040  R-HSA-445717
 R-HSA-5358351  R-HSA-5610787  R-HSA-5654219  R-HSA-5654221  R-HSA-5654227
 R-HSA-5654228  R-HSA-5654687  R-HSA-5654696  R-HSA-5654708  R-HSA-5654716
 R-HSA-5654736  R-HSA-5654738  R-HSA-5654741  R-HSA-5654743  R-HSA-983231
 S54705  S54707  S54709  S54711  SM00100
 SM00394  uc002jhg.5  uc002jhh.5  uc002jhi.5  uc002jhj.5
 uc002jhl.5  uc031ref.2  UPI0000001C57  UPI000040A1C2  XM_011524983
 XM_011524984  XM_011524985  XP_011523285  XP_011523286  XP_011523287
 Y07642
Secondary Identifiers KAP0_HUMAN, K7ER48, Q567S7
Gene Names PRKAR1A, PKR1, PRKAR1, TSE1
Chain initiator methionine:1, chain:1-381, chain:2-381
This entry is a component of:
hasMember
Reference Genes
Database Identifier
dbSNP Gene 5573
CTD Gene 5573
BioGPS Gene 5573
NCBI Gene 5573
ENSEMBL ENSG00000108946
KEGG Gene PRKAR1A
Orphanet 15139
Reference Transcripts
Database Identifier
RefSeq NM_212471
Cross References
Database Identifier
RefSeq NP_997636, NP_001265362, NP_001263218, NP_001263219, NP_002725, NP_997637
ZINC_target P10644
HMDB_protein HMDBP02560
PRO P10644
GeneCards P10644
UCSC human P10644
Interactions
Confidence Score Interactor Accession Interactor Name Evidence
0.779 P17612 KAPCA_HUMAN 4
0.702 CHEBI:17489 3',5'-CYCLIC AMP 3
0.645 P03259-2 5
0.621 Q9H8W4 PKHF2_HUMAN 3
0.556 P27344 DPB3_YEAST 3
0.556 P38756 TCD1_YEAST 3
0.544 Q9H0R8 GBRL1_HUMAN 2
0.524 P35250 RFC2_HUMAN 7
0.524 Q01105 SET_HUMAN 2
0.508 P51817 PRKX_HUMAN 2
0.499 CHEBI:64403 8-AHA-CAMP 6
0.499 CHEBI:64404 8-AHA-OMETHYLADENOSINE 4