Reactome: A Curated Pathway Database

Post-translational protein modification

Stable Identifier
R-HSA-597592
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

After translation, many newly formed proteins undergo further covalent modifications that alter their functional properties and that are essentially irreversible under physiological conditions in the body. These modifications include the internal peptide bond cleavages that activate proenzymes, the attachment of oligosaccharide moieties to membrane-bound and secreted proteins, the attachment of lipid or glycolipid moieties that serve to anchor proteins to cellular membranes, and the vitamin K-dependent attachment of carboxyl groups to glutamate residues.

Participants
Participant Of
Orthologous Events