Reactome | TRPC5 [plasma membrane]

TRPC5 [plasma membrane]

Stable Identifier

R-HSA-612170

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Short transient receptor potential channel 5, TRPC5_HUMAN

Locations in the PathwayBrowser

Expand all

Developmental Biology (Homo sapiens)

- Nervous system development (Homo sapiens)
  - Axon guidance (Homo sapiens)
    - Netrin-1 signaling (Homo sapiens)
      - Role of second messengers in netrin-1 signaling (Homo sapiens)
        
        Activation of TRPC channels by Netrin-1 (Homo sapiens)
        
        Activated TRP channels [plasma membrane] (Homo sapiens)
        
        TRPC1+4/5 [plasma membrane] (Homo sapiens)
        
        TRPC4/5 [plasma membrane] (Homo sapiens)
        
        TRPC5 [plasma membrane] (Homo sapiens)
        
        TRPC channels [plasma membrane] (Homo sapiens)
        
        TRPC1+4/5 [plasma membrane] (Homo sapiens)
        
        TRPC4/5 [plasma membrane] (Homo sapiens)
        
        TRPC5 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9UL62 TRPC5

Gene Names

TRPC5, TRP5

Chain

chain:1-973

Reference Genes

BioGPS Gene:7224 TRPC5

COSMIC (genes):TRPC5 TRPC5

CTD Gene:7224 TRPC5

dbSNP Gene:7224 TRPC5

ENSEMBL:ENSG00000072315 TRPC5

ENSEMBL_homo_sapiens_GENE:ENSG00000072315.4 TRPC5

HGNC:12337 TRPC5

KEGG Gene (Homo sapiens):7224 TRPC5

Monarch:7224 TRPC5

NCBI Gene:7224 TRPC5

OMIM:300334 TRPC5

UCSC:Q9UL62 TRPC5

Reference Transcript

Other Identifiers

11737501_at

11737502_at

1559057_PM_at

1559057_at

17113398

220552_PM_at

220552_at

3510152

4018324

4018326

4018328

4018329

4018330

4018331

4018332

4018337

4018339

4018342

4018343

4018348

4018355

4018356

4018357

4018358

4018369

4018370

4018371

4018372

4018373

49966_at

7224

8174556

A_23_P254989

GE536288

GO:0003779

GO:0005215

GO:0005216

GO:0005262

GO:0005515

GO:0005886

GO:0006811

GO:0006816

GO:0007204

GO:0007399

GO:0008092

GO:0008284

GO:0010800

GO:0012501

GO:0015279

GO:0016020

GO:0030154

GO:0030182

GO:0030276

GO:0030425

GO:0030426

GO:0034220

GO:0034703

GO:0034704

GO:0036211

GO:0042805

GO:0043025

GO:0045666

GO:0045773

GO:0048856

GO:0050774

GO:0051117

GO:0051402

GO:0051480

GO:0055065

GO:0055085

GO:0061024

GO:0070588

GO:0070679

GO:0070782

GO:1902630

HMNXSV003009164

ILMN_1772242

ILMN_1902109

PH_hs_0013121

TC0X001284.hg

g6912735_3p_at

Participates

as a member of

Inferred To

TRPC5 [plasma membrane] (Bos taurus)

TRPC5 [plasma membrane] (Canis familiaris)

TRPC5 [plasma membrane] (Gallus gallus)

TRPC5 [plasma membrane] (Sus scrofa)

Trpc5 [plasma membrane] (Mus musculus)

Trpc5 [plasma membrane] (Rattus norvegicus)

trp [plasma membrane] (Drosophila melanogaster)

trp-2 [plasma membrane] (Caenorhabditis elegans)

trpc5 [plasma membrane] (Xenopus tropicalis)

Homologues of TRPC5 [plasma membrane] (Drosophila melanogaster)

Trpgamma [plasma membrane] (Drosophila melanogaster)

Cross References

RefSeq

XP_016885263.1, NP_036603.1

Guide to Pharmacology - Targets

490

OpenTargets

ENSG00000072315

GeneCards

Q9UL62

HPA

ENSG00000072315-TRPC5

Ensembl

ENSG00000072315, ENSP00000262839, ENST00000262839

PRO

Q9UL62

Pharos - Targets

Q9UL62

Orphanet

25005

PDB

8GVW, 6YSN, 8GVX, 7X6C, 7WDB, 7D4Q, 7E4T, 7D4P, 7X6I

HMDB Protein

HMDBP08077